Crypto & Macro Brief: U.S.–China Trade Mechanism, Trump Pharma Cuts, and Institutional Moves

12.05.2025

This week’s key developments span geopolitics and crypto: the U.S. and China agreed to establish a trade consultation mechanism in Switzerland, Trump vowed steep cuts to prescription drug prices, and institutions like JPMorgan and WLFI ramped up crypto positions. Meanwhile, Lido DAO addresses an oracle breach, Berachain refines its Proof-of-Liquidity protocol, and thought leaders weigh in on Bitcoin’s dominance.

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U.S.–China Forge Trade Consultation Mechanism

“Big Progress” in Geneva: Vice Premier Li described the Switzerland talks as “constructive,” with both sides agreeing to create a formal mechanism for ongoing trade consultations. A joint statement is due Monday, promising “great news for the world.” .
Market Impact: Renewed U.S.–China dialogue often boosts risk assets, from equities to crypto, as tariff uncertainty recedes.

Trump’s Prescription Drug Price Slashes

30–80% Cuts Pledged: President Trump announced an executive order to cap U.S. prices on prescription and pharmaceutical goods at the lowest global rate, targeting a 30–80% reduction. The order is expected today at 16:00 MSK. .
Broader Implications: Lower drug costs could reduce consumer inflation measures—potentially easing future Fed policy pressure.

Institutional Crypto Accumulation

JPMorgan’s Bitcoin ETF Stake: According to SEC filings, JPMorgan increased its holdings in the BlackRock Bitcoin ETF to $1.7 billion, underscoring mounting institutional confidence. .
WLFI Pectra Upgrade & Aave Activity: The Trump-linked World Liberty Financial (WLFI) proudly launched Ethereum’s Pectra upgrade, touting improved scalability and security. Within eight hours, WLFI deposited 50 WBTC into Aave, took out $4 million USDC, and purchased 1,590 WETH at an average price of $2,515—demonstrating aggressive DeFi deployment. .

Protocol Security & Upgrades

Lido DAO Emergency Vote: Following an oracle compromise at Chorus One, Lido DAO called an emergency governance vote to replace the affected oracle, isolating the issue without overhauling the entire staking platform. .
Berachain PoL v1.1: The Berachain community unveiled Proof-of-Liquidity v1.1, optimizing BERA incentives via fee-backed liquidity, lowering participation thresholds, and reallocating BEX fees to strengthen ecosystem revenue and token holder value.

Market Sentiment & Thought Leadership

Arthur Hayes on Trade Deal: Former BitMEX CEO Arthur Hayes believes the upcoming U.S.–China trade agreement will look impressive politically but lack substantive economic heft. .
Willy Woo on Bitcoin Dominance: On-chain guru Willy Woo notes that altcoins’ combined market cap ($10.5 trillion) pales beside Bitcoin’s $100+ trillion network value. He predicts Bitcoin will command over 90% dominance, that crypto VC funding will vanish, and advises buying BTC and investing in its infrastructure.

Security Incidents & Legal Action

Discord Ledger Phishing Hack: Attackers compromised a Ledger Discord mod’s account to distribute phishing links aimed at stealing user seed phrases—highlighting ongoing DeFi security risks. .
BSV vs. Binance Lawsuit: BSV investors revived a £10 billion ($13 billion) lawsuit against Binance, alleging the 2019 delisting devastated BSV’s price.

CONCLUSION

The week blends high-level diplomacy with actionable crypto developments: as U.S.–China trade dialogue ramps up, Trump’s policy pivots and institutional inflows bolster bullish narratives. At the same time, protocol governance and security incidents underscore the need for robust risk management. Moving forward, traders should track the Monday joint statement, watch drug-price reforms for macro cues, and monitor on-chain flows into DeFi and Bitcoin ETFs for the next market catalyst.

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